Hyaluronic Acid: Best Skincare Products That Really Work

In the ever-evolving realm of skincare, the spotlight has increasingly turned towards one powerhouse ingredient – Hyaluronic Acid. Renowned for its unparalleled ability to hydrate and plump the skin, hyaluronic acid has become a staple in the beauty industry. This article delves into the world of hyaluronic acid products, exploring their efficacy, safety, and specific applications. From addressing common skincare concerns to targeting scars, we will unravel the secrets behind the best hyaluronic acid-infused formulations that genuinely work wonders. Join us on this journey as we also explore the innovative realm of nano cosmetics, where the fusion of science and skincare takes center stage. Let's navigate through the myriad of options to discover the top-tier products that harness the power of hyaluronic acid for radiant and revitalized skin.

Kyselina hyaluronová a pleť jak vybrat správnou kosmetiku 

Functions of hyaluronic acid in the body

Hyaluronic acid is a type of saccharide that (in the form of so-called hyaluronate) naturally occurs, among other things, in cartilage, lips and intercellular matter. Half of the total amount of hyaluronic acid in the human body is in the skin, especially in its upper part - the skin.

The compound is renowned for its anti-aging, moisturizing and healing effects. Its molecules have a round shape and can absorb a huge amount of water. Hyaluronic acid is thus found in the body in the form of a gel, which gives tissues elasticity and the ability to absorb shocks. It is therefore no coincidence that this substance is a basic component of joint fluid.

In the skin, hyaluronic acid ensures the passage of nutrients and fluids and thus participates in nutrition and hydration. Thanks to its ability to bind water, it also slows down its loss (evaporation) through the skin pores. This substance plays an important role in healing, when it allows blood components and cells of the immune system to reach the injured skin.

The aforementioned abilities of hyaluronic acid were confirmed by e.g. 2014 study published in the scientific periodical The Journal of Clinical and Aesthetic Dermatology . Women who applied the product with this substance to their skin twice a day noticed after 8 weeks up to a 40% reduction in the depth of wrinkles and an increase in firmness and skin elasticity by up to 55%.How does hyaluronic acid work to reduce wrinkles?

8 Effects of Hyaluronic Acid on the Skin:

  • Hydrates the skin,
  • Accelerates healing,
  • Strengthens the natural skin barrier,
  • Increases skin resistance to negative influences,
  • Reduces wrinkles,
  • Smoothens the skin,
  • Promotes cell regeneration in the skin,
  • Helps with blackheads and pigmentation.



How does hyaluronic acid hydrate the skin?

As we age, our skin's ability to retain moisture decreases, making it crucial to replenish it. Hyaluronic acid has become extremely popular in recent years because it can retain up to 1000 times its own weight in water.

How Hyaluronic Acid Reduces Wrinkles and Fights Dry Skin: Tips for Optimal Use

Hyaluronic acid is a powerful ingredient in skincare that binds and attracts moisture from its surroundings. However, if you have dry skin, it's important to properly prepare your skin before application to ensure maximum benefits. Start by applying a toner or moisturizing mist, then apply the hyaluronic acid and seal it with a moisturizer after absorption.


Combatting Fine Lines and Wrinkles with Hyaluronic Acid

Hyaluronic acid is a potent ingredient that helps reduce the appearance of fine lines and wrinkles by keeping the skin moisturized and promoting increased skin cell production. Applying an eye serum or a hydrating nanofiber eye mask can help prevent the formation of new wrinkles and reduce the appearance of existing ones by up to 75%.

Hyaluronic Acid and Pigmentation Spots

While hyaluronic acid can aid in reducing the appearance of age and pigment spots through increased cell turnover, it's not a standalone solution. Combining it with vitamin C, such as in a hydrating nanofiber mask, is essential for effectively treating dark spots.

Hyaluronic acid has numerous positive effects on the skin, including:

  • Transferring minerals, vitamins, amino acids and other active substances to the depth of the skin
  • Helping to suppress acne and skin inflammation
  • Reducing skin redness
  • Suppressing free radicals that are created by the sun's UV radiation and can lead to skin cell damage and cancer.

The bad news is that the amount of this compound in the body decreases with age, which can be further accelerated by an unhealthy lifestyle, especially smoking and alcohol consumption.

Luckily, there are a variety of cosmetic products that can supplement hyaluronic acid and restore the youthful appearance of the skin. But before you choose a product, it's important to understand the different types of hyaluronic acid and their advantages.

Low- and high-molecular hyaluronic acid differ in how they are absorbed into the skin. In the body, hyaluronic acid occurs as a molecule in which disaccharide units are linked one after the other, similar to beads on a thread. The more units there are, the bulkier the molecule, making it harder to penetrate the skin. The type of hyaluronic acid affects the effectiveness of the relevant cosmetic product.

Hyaluronic acid is generally divided into two types:

  • Low molecular (also referred to as nanomolecular) – in this form, hyaluronic acid penetrates to a greater depth and lasts longer. It helps remove deep-seated wrinkles, hydrates the deeper layers of the skin, and gives them elasticity.
  • High molecular weight – this type of hyaluronic acid sticks to the surface and works for a shorter time. It eliminates small wrinkles and hydrates the visible part of the skin.

When choosing a cosmetic product with hyaluronic acid, keep these tips in mind:

  • Choose products with no more than 2% hyaluronic acid – higher concentrations can paradoxically dry out your skin.
  • Make sure that hyaluronic cosmetics contain occlusive substances of an oily nature that prevent water from escaping from the skin. Commonly used occlusives include bamboo butter, beeswax, or coconut oil.

Can Hyaluronic Acid be effective against acne and acne scars?

While Hyaluronic acid may not be able to fill in visible acne scars, it can help to reduce redness caused by acne. Its ability to protect the skin is especially helpful for acne-prone skin, as such skin is generally lacking a strong lipid barrier. Additionally, hyaluronic acid can aid in controlling sebum production, making it a potentially useful ingredient for preventing acne breakouts. To actively fight acne, consider trying a serum that combines hyaluronic acid and salicylic acid.

Best Hyaluronic Acid Products to Nourish and Rejuvenate Your Skin

product name

type of hyaluronic acid



Hyaluron eye serum NAFIGATE

low molecular weight

unperfumed serum with Revitalin RF (mixture of substances for skin nutrition); also suitable for sensitive skin

revitalization of the eye area, turning off the skin and brightening the circles under the eyes; for men and women from 25 years

Hyaluronic eye cream NAFIGATE

high molecular weight

unperfumed cream with chlorella and almond and oat oil; also suitable for sensitive skin

hydration of the eye area, reduction of swelling; for men and women from 25 years

NAFIGATE Hyaluron Serum

low molecular weight, 2% concentration

unperfumed serum; also suitable for sensitive skin

reduction of wrinkles and scars, hydration and increase in strength and elasticity of the skin; for men and women from 25 years

NAFIGATE lifting serum with hyaluronan

low molecular weight, 2% concentration

unperfumed serum with plant leaf extract Bulbine frutescen (Liftonin Xpert complex); also suitable for sensitive skin

reduction of wrinkles and scars, hydration and increase in strength and elasticity of the skin, support for collagen production;</ p>

for men and women from 40

Hyaluronic serum for wrinkle reduction 50+ NAFIGATE

low molecular weight

unperfumed serum with millet extract; also suitable for sensitive skin

reduction of wrinkles and scars, hydration and increase of strength and elasticity of the skin, support of collagen and keratin formation; for men and women from 50

Hyaluron moisturizing day cream SPF 15 NAFIGATE

high molecular weight

unperfumed cream with red algae, argan oil and vitamins A and E; also suitable for sensitive skin

skin hydration and its protection from sunlight; for men and women from 30

Moisturizing Dry Sheet Nanofiber Face Mask [n]fibrecare

low molecular weight

A revolutionary dry platinum nanofiber mask for professional home care, extremely popular in beauty salons today</p >

Gives skin freshness, supports collagen production and brightens skin. For women 25+.


Hyaluronic Acid Internally: Try Dietary Supplements

Hyaluronic acid is also used as a dietary supplement in the form of capsules or gel. It helps keep joints healthy and flexible and can reduce pain and swelling associated with arthritis or other joint problems.

Read also about: How to Prevent Wrinkles: Tips for Maintaining Youthful Skin


For Whom is Hyaluronic Acid Suitable?

Hyaluronic acid is suitable for anyone who needs to increase skin hydration. It is perfect for all skin types, especially mature, dry, dehydrated, sagging skin suffering from signs of aging, and acne-prone and problematic skin. Hyaluronic acid is ideal for women and men of all ages. It is recommended to start using hyaluronic acid from the age of 25 for prevention, but it can be used earlier if your skin shows signs of aging.

Is Hyaluronic Acid Suitable for Oily Skin?

Yes! Hyaluronic acid is a great choice for oily skin because it does not clog pores or leave a heavy residue, while still providing a significant amount of hydration. It also helps regulate sebum production, making it an ideal ingredient for oily skin seeking hydration and wrinkle smoothing.

Does Hyaluronic Acid Have Side Effects?

Allergic reactions to hyaluronic acid are extremely rare since it is the body's own substance. If any symptoms of allergy occur, it is usually a reaction to one of the accompanying substances in the cosmetic product. To avoid side effects, it is recommended to test the serum or ointment on a small piece of skin before application.

While injection application has a higher risk of side effects, it is preferable to try a more conservative approach with cosmetic products.

How to Use Hyaluronic Acid Properly?

To use hyaluronic acid properly, never apply it to dry skin. Always apply a toner or moisturizing mist first. After application, let the serum dry and use a moisturizer. This is true whether you use hyaluronic acid serum or more effective nanofiber mask.

What Can Hyaluronic Acid Be Safely Combined With?

Hyaluronic acid is an extremely versatile ingredient and compatible with most active ingredients used in cosmetics, including retinol, vitamin C, and alpha-hydroxy acids (AHA).

How long does it take for hyaluronic acid to work?

The effects of hyaluronic acid can be seen immediately, as it is a hydrating ingredient that helps to plump and smooth the skin. However, the long-term effects may take several weeks or even months to become apparent, as hyaluronic acid helps to improve the overall health and appearance of the skin over time.

How often should you use hyaluronic acid?

It is generally recommended to use hyaluronic acid once or twice daily, depending on the specific product and your individual skin needs. However, it is important to follow the instructions on the product and to not overuse it, as using too much hyaluronic acid can lead to dryness and irritation.

Can you use too much hyaluronic acid on your skin?

While hyaluronic acid is generally considered safe and well-tolerated, using too much of it can lead to dryness and irritation. It is important to follow the instructions on the product and to not overuse it, and to always follow up with a moisturizer to lock in the hydration provided by the hyaluronic acid.

Can hyaluronic acid be used in combination with other skincare ingredients?

Yes, hyaluronic acid is a versatile ingredient that can be used in combination with many other skincare ingredients, such as vitamin C, retinol, and alpha-hydroxy acids. However, it is important to be aware of any potential interactions or contraindications, and to always patch test new products before use.

Is hyaluronic acid safe to use during pregnancy or while breastfeeding?

While there is limited research on the safety of hyaluronic acid during pregnancy or while breastfeeding, it is generally considered safe for topical use. However, it is always best to consult with a healthcare professional before using any new skincare product while pregnant or breastfeeding.

Can hyaluronic acid be used on sensitive skin?

Yes, hyaluronic acid is generally considered safe and well-tolerated, even for those with sensitive skin. However, it is always best to patch test new products before use, and to be aware of any potential interactions or contraindications.

How does hyaluronic acid differ from other popular skincare ingredients like retinol or vitamin C?

Hyaluronic acid is primarily a hydrating ingredient that helps to plump and smooth the skin, while retinol and vitamin C are primarily used for their anti-aging and brightening properties, respectively. However, all of these ingredients can be used in combination to provide a comprehensive skincare routine that addresses multiple concerns.

What to Take Away from the Article?

  • Hyaluronic acid has moisturizing and healing effects and helps reduce acne.
  • It acts like a gel that absorbs shocks, smoothes the skin, and maintains its elasticity.
  • Low-molecular hyaluronic acid (in the form of a serum) is suitable for deep hydration and wrinkle smoothing. High-molecular weight hyaluronic acid (in the form of a cream) is suitable for hydrating and exfoliating the skin's surface.
  • Choose cosmetics with no more than 2% hyaluronic acid and the addition of shea butter, coconut oil, or other oily compounds that lock in moisture in the skin.


  • Hyaluronic acid: A key molecule in skin aging
  • Functions of hyaluronan in wound repair
  • Interactions of hyaluronic acid with the skin and implications for the dermal delivery of biomacromolecules
  • Efficacy of a New Topical Nano-hyaluronic Acid in Humans
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